| 丙硫异烟胺的热稳定性及其热分解动力学 |
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| 引用本文： | 王韶旭,赵哲,谭志诚,李彦生,童波,史全,李英.丙硫异烟胺的热稳定性及其热分解动力学[J].物理化学学报,2007,23(9):1459-1462. |
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| 作者姓名： | 王韶旭 赵哲 谭志诚 李彦生 童波 史全 李英 |
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| 作者单位： | College of Environmental Science &Chemical Engineering, Dalian Jiaotong University, Dalian 116028, Liaoning Province, P. R. China; Thermochemistry Laboratory, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, Liaoning Province, P. R. China |
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| 摘 要： | 通过热重法研究了抗结核药物丙硫异烟胺的热稳定性, 计算了该药物的动力学参数并建立了热分解动力学方程. 用Kissinger和Ozawa-Flynn-Wall两种方法计算该药物热分解过程的活化能Ea=54.65 kJ·mol-1. 用Malek法推断该药物的动力学机理函数及指前因子A, 其结果分别为f(α)=α0.391(1-α)0.145, lnA=13.12. 此外, 用差热法测定该物质的熔点、摩尔熔化焓和摩尔熔化熵, 分别是414.09 K、23.21 kJ·mol-1和56.06 J·mol-1·K-1.
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| 关 键 词： | 丙硫异烟胺 热分解动力学 热重分析 差热分析 热力学性质 |
| 收稿时间： | 2007-03-27 |
| 修稿时间： | 2007-03-27 |
Thermal Stability and Kinetics of Thermal Decomposition for Protionamide |
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| WANG Shao-Xu,ZHAO Zhe,TAN Zhi-Cheng,LI Yan-Sheng,TONG Bo,SHI Quan,LI Ying.Thermal Stability and Kinetics of Thermal Decomposition for Protionamide[J].Acta Physico-Chimica Sinica,2007,23(9):1459-1462. |
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| Authors: | WANG Shao-Xu ZHAO Zhe TAN Zhi-Cheng LI Yan-Sheng TONG Bo SHI Quan LI Ying |
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| Institution: | College of Environmental Science &Chemical Engineering, Dalian Jiaotong University, Dalian 116028, Liaoning Province, P. R. China; Thermochemistry Laboratory, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, Liaoning Province, P. R. China |
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| Abstract: | The thermal stability and the kinetics of thermal decomposition of protionamide were studied by thermogravimetry. Activation energy Ea of thermal decomposition of this substance was obtained to be 54.65 kJ·mol-1 by Kissinger method and Ozawa-Flynn-Wall method. Kinetics model function and frequency factor A of protionamide were predicted with the Malek method, which were f(α)=α0.391(1-α)0.145 and lnA=13.12, respectively. Moreover, melting point, molar enthalpy and entropy of fusion of this compound were determined to be 414.09 K, 23.21 kJ·mol-1, and 56.06 J·mol-1·K-1, respectively. |
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| Keywords: | Protionamide Kinetics of thermal decomposition Thermogravimetry Differential thermal analysis Thermodynamic property |
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