|
|||||
|
|
The chemistry of cyclic enaminoketones. III. Synthesis of bi- and tricyclic enaminoketones from enamine esters and nitriles |
|
| Authors: | A I Meyers A H Reine J C Sircar K B Rao S Singh H Weidmann M Fitzpatrick |
| Abstract: | The cyclization of enamines derived from β-aminoesters and β-aminonitriles into bi- and tricyclic enaminoketones ( 6,9,13 and 24 ) has been investigated. The enamines derived from aminonitriles cyclize smoothly with magnesium perchlorate in benzene or toluene, whereas the enamines derived from aminoesters cyclize spontaneously during their formation. The scope and limitation of this process is discussed. |
| Keywords: | |