Abstract: | Abstract A simple, efficient, and practical procedure for the synthesis of various substituted 2,3-dihydro-2-phenyl-1H-naphtho1,2-e]1,3]oxazines and 3,4-dihydro-3-phenyl-2H-naphtho2,1-e]1,3]oxazines using KAl(SO4)2 12H2O (alum) as a non-toxic, reusable, inexpensive, and easily available catalyst is described using water as a solvent. These improved reaction conditions allow the preparation of a wide variety of substituted 1,3]oxazines in high yields and purity under mild reaction conditions. |