| 基于核酸分子识别的电化学分析方法与应用 |
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| 引用本文： | 周殿明,蒋健晖,沈国励,俞汝勤.基于核酸分子识别的电化学分析方法与应用[J].电化学,2011,17(3):242-248. |
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| 作者姓名： | 周殿明 蒋健晖 沈国励 俞汝勤 |
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| 作者单位： | 化学生物传感与计量学国家重点实验室，湖南大学化学化工学院，湖南 长沙 410082 |
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| 基金项目： | 国家自然科学基金(21025521,21035001,20875027)资助 |
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| 摘 要： | 核酸作为生物体遗传信息的载体以及分子生物学和生物分析化学中重要的功能分子，近年来在电化学分析中受到了越来越多的重视。本文以作者所在研究组的工作为实例，对核酸分子识别的电化学分析方法作出简要的评述，内容涉及核酸序列和基因变异的电化学分析以及核酸作为功能分子进行识别检测的电化学分析等等。
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| 关 键 词： | 电化学分析 核酸 分子识别 |
| 收稿时间： | 2011-06-07 |
Electrochemical Analysis based on Molecular Recognition of Nucleic Acids and its Applications |
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| ZHOU Dian-ming,JIANG Jian-hui,SHEN Guo-li,YU Ru-qin.Electrochemical Analysis based on Molecular Recognition of Nucleic Acids and its Applications[J].Electrochemistry,2011,17(3):242-248. |
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| Authors: | ZHOU Dian-ming JIANG Jian-hui SHEN Guo-li YU Ru-qin |
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| Institution: | ZHOU Dian-ming,JIANG Jian-hui,SHEN Guo-li,YU Ru-qin(State Key Laboratory of Chemo/Biosensing and Chemometrics,College of Chemistry and Chemical Engineering,Hunan University,Changsha 410082,China) |
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| Abstract: | Nucleic acid as the carrier of genetic information and the functional molecules for molecular biology and bioanalytical chemistry has attracted increasing interest in electrochemical analysis.This review presents a brief outline of some electrochemical analytical assays based on molecular recognition of nucleic acids.Most of these methods are focused on the detection of nucleic acid sequence,genetic mutation and nucleic acids as functional molecules. |
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| Keywords: | electrochemical analysis nucleic acids molecular recognition |
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