Direct Synthesis of Allylic Thioethers Under Greener Conditions: A Solvent- and Catalyst-Free Approach |
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| Authors: | Greice Tabarelli Marcelo Godoi Rômulo F S Canto José R Mora Faruk Nome |
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| Institution: | 1. Departamento de Química , Universidade Federal de Santa Catarina , Florianópolis , Brazil;2. Escola de Química e Alimentos , Universidade Federal do Rio Grande–Campus Santo Ant?nio da Patrulha , Brazil |
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| Abstract: | We present herein a new catalyst-free and solvent-free approach for the synthesis of allylic thioethers directly from allylic alcohols and thiols. The methodology allows the synthesis of different allylic thioethers in good to excellent yields under microwave irradiation. Theoretical calculations for the allylic carbocation helped to explain the regioselectivity observed when nonsymmetric substrates are used in the reaction. |
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| Keywords: | Allylic thioethers catalyst-free green chemistry solvent-free |
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