Formation of Vesicles from Amphiphilic Random Copolymers in Solution: A Dissipative Particle Dynamics Simulation Study |
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| Authors: | Meiling Chen Meng Sun Lixiang Wang Xiaoya Liu |
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| Institution: | Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering , Jiangnan University , Wuxi , P. R. China |
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| Abstract: | Five coarse-grained models were built for amphiphilic random copolymers. The self-assembly of amphiphilic random copolymers in selective solvent was investigated via dissipative particle dynamics simulations. The simulation results showed that the content of hydrophilic particles and the repulsive parameter between solvent and copolymer particles were two key factors of the vesicle formation. We report herein on how to control the self-assembled morphology evolution. The two mechanisms of vesicle formation from amphiphilic random copolymers are found through investigating the dynamic processes of vesicle formation, which is in accordance with the experiment and simulation results of amphiphilic block copolymer reported in the literature.  |
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| Keywords: | Amphiphilic dissipative particle dynamics random copolymer self-assembly vesicle |
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