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Synthesis,Spectral Characterization,and Antimicrobial Activities of Schiff Base Complexes Derived From 4-Aminoantipyrine
Authors:B. Manjula  C. Justin Dhanaraj
Affiliation:1. PG and Research Department of Chemistry , Presidency College , Chennai , Tamil Nadu , India;2. Department of Chemistry , Anna University College of Engineering , Nagercoil , Tamil Nadu , India
Abstract:
Novel cobalt (II), nickel (II), copper (II), and zinc (II) complexes were synthesized from Schiff base ligand derived from 4-aminoantipyrine, vanillin, and o-anisidine. The structural features were derived from their elemental analysis, molar conductance, magnetic measurements, and various spectroscopic techniques such as infrared, ultraviolet visible, nuclear magnetic resonance, and electron paramagnetic resonance spectroscopy. Antimicrobial screening tests were performed against bacteria and fungi. The comparative study of the minimum inhibitory concentration values of the Schiff base and its metal complexes indicate that the metal complexes exhibit greater antimicrobial activity than the free ligand.
Keywords:4-aminoantipyrine  o-anisidine  Schiff base  ultraviolet visible  vanillin
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