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Yellow emissive carbon dots in ludox silica matrix with anticancer activity for enhanced imaging of developed sweat latent fingermarks
Authors:S Kainth  V Sharma  M Bhagat  S Basu
Institution:1. School of Chemistry and Biochemistry, Affiliate Faculty—TIET-Virginia Tech Center of Excellence in Emerging Materials, Thapar Institute of Engineering and Technology, Patiala 147004, India;2. Institute of Forensic Science & Criminology, Panjab University, Chandigarh 160014, India;3. School of Biotechnology, University of Jammu, Jammu 180006-180006, India
Abstract:The recognition of fingermarks plays a vital role during a criminal investigation. In the current scenario, fluorescent nano-powders emerged as a potential candidate for latent fingermark detection. We pioneer the use of microwave technology for the synthesis of carbon dots (CDs) with the cationic surfactant (cetylpyridinium chloride). The surfactant-derived CDs exhibit yellow fluorescence and emission at 545 nm with high quantum yield of (QY~34%). The prepared CDs also demonstrated amphiphilic properties. These luminous CDs were combined with ludox HS-30 to develop fluorescent hybrid nano-powders for the detection of sweat latent fingermarks on a non-porous surface. The ludox@CDs accumulate particle size 11.36 ± 1.235 nm and surface area 111 cm3/g?1. The fluorescent hybrid nano-powders emerged to be successful in creating high contrast and accurate latent fingermark images. Furthermore, cytotoxicity studies on breast cell lines (fR-2 and MCF-7) were conducted by using ludox@CDs. The results revealed that ludox@CDs were less toxic and biocompatible in comparison to the commercialized dusting reagents. Fortunately, ludox@CDs demonstrated anticancer efficacy against MCF-7 breast cancer cell lines. Thus, our findings herald a new age for fluorescent hybrid nano-powders in criminal investigation and biomedical applications.
Keywords:Carbon dots  Ludox HS-30  Cytotoxicity  Fingermark detection  Antitumor
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