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Review on recent applications of the liquid waveguide capillary cell in flow based analysis techniques to enhance the sensitivity of spectroscopic detection methods
Authors:Ricardo N.M.J. Pá  scoa,Ildikó   V. Tó  th,Antó  nio O.S.S. Rangel
Affiliation:1. CBQF/Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal;2. REQUIMTE, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal
Abstract:
Incorporation of long path length liquid waveguide capillary cell (LWCC or LCW) into spectrometric detection systems can increase the sensitivity of these by orders of magnitude (up to 500 times), and consequently can reduce the detection limits. The combination of the long path length spectrophotometry with flow methodologies can provide analytical solutions for various challenges in the field of environmental, biochemical and food chemistry.
Keywords:Liquid core waveguide (LCW)   Liquid waveguide capillary cell (LWCC)   Spectrophotometric methods   Flow analysis   Long path-length spectrophotometry   Nanomolar detection limit
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