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The use of protium and deuterium analogues in mechanistic studies of thiazole syntheses
Affiliation:1. Laboratory of Lipidomics and Bioorganic, Bioforensics Research Group, Federal University of Pelotas, 96010 900 Pelotas, RS, Brazil;2. Identification Group, Brazilian Federal Police, 90610-093 Porto Alegre, RS, Brazil;3. Materials Science and Engineering, Technology Development Center, Federal University of Pelotas, 96010-000 Pelotas, RS, Brazil;4. Post-Graduate Program in Dentistry, Department of Restorative Dentistry, Dental School, Federal University of Pelotas, 96010 Pelotas, RS, Brazil;5. National Institute of Forensic Science and Technology (INCT Forensic), Porto Alegre (RS), Pelotas (RS), Brazil;6. Laboratory of Biochemistry Research and Molecular Biology of Microorganisms (LaPeBBiOM), Federal University of Pelotas, 96010-900 Pelotas, RS, Brazil;7. Pharmacosciences Department, Federal University of Health Sciences of Porto Alegre, Porto Alegre, RS, Brazil
Abstract:
The mechanisms of two reactions which give isomeric thiazol-5-yl ketones have been elucidated by work with substrates containing pairs of acyl groups and their deuterium-substituted analogues.
Keywords:
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