Radical cyclization via dichloromethyl radical. Stereoselective synthesis of cis-2,4-disubstituted pyrrolidine derivatives. |
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| Affiliation: | 1. OncoArendi Therapeutics SA, Żwirki i Wigury 101, 02-089 Warsaw, Poland;2. Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Ks. Trojdena 4, 02-109 Warsaw, Poland;3. Department of Immunology, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland;1. School of Pharmacy, Fudan University, Shanghai 201203, China;2. State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai 201203, China;1. School of Pharmaceutical Sciences, College of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, 920-1192, Japan;2. Graduate School of Pharmacy, Meijo University, Tempaku-ku, Nagoya, 468-8503, Japan;3. Molecular Pharmacology Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, 21702, United States;4. Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 27599-7568, United States;1. Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, PO Box 368, Ridgefield, CT 06877-0368, USA;2. Evotec (UK) Ltd, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, United Kingdom;3. Evotec AG, Manfred Eigen Campus, Essener Bogen 7, 22419 Hamburg, Germany |
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