Domino reaction for the chemo- and stereoselective synthesis of trans-2,3-dihydrobenzofurans from N-thiophosphinyl imines and sulfur ylides |
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Authors: | Xie Peizhong Wang Liye Yang Lihua Li Erqing Ma Jianze Huang You Chen Ruyu |
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Institution: | State Key Laboratory and Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China. |
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Abstract: | A novel domino annulation between sulfur ylides and salicyl N-thiophosphinyl imines was developed. The method allows the synthesis of a highly substituted trans-2,3-dihydrobenzofuran skeleton with high yield and excellent chemo- and stereoselectivity. |
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