Inhibition of Acinetobacter baumannii biofilm formation on a methacrylate polymer containing a 2-aminoimidazole subunit |
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Authors: | Peng Lingling DeSousa Joseph Su Zhaoming Novak Bruce M Nevzorov Alexander A Garland Eva R Melander Christian |
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Affiliation: | North Carolina State University, Department of Chemistry, Raleigh, North Carolina, 27695-8204, USA. |
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Abstract: | A polymeric composite containing a 2-aminoimidazole derivative was synthesized. It was found that this polymer was resistant to biofilm colonization by Acinetobacter baumannii, no leaching of the 2-aminoimidazole derivative was observed after 2 weeks of treatment with deionized water, and the resulting polymer was not hemolytic. |
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