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Inhibition of Acinetobacter baumannii biofilm formation on a methacrylate polymer containing a 2-aminoimidazole subunit
Authors:Peng Lingling  DeSousa Joseph  Su Zhaoming  Novak Bruce M  Nevzorov Alexander A  Garland Eva R  Melander Christian
Institution:North Carolina State University, Department of Chemistry, Raleigh, North Carolina, 27695-8204, USA.
Abstract:A polymeric composite containing a 2-aminoimidazole derivative was synthesized. It was found that this polymer was resistant to biofilm colonization by Acinetobacter baumannii, no leaching of the 2-aminoimidazole derivative was observed after 2 weeks of treatment with deionized water, and the resulting polymer was not hemolytic.
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