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Synthesis of thiophenes and pyranone fused thiophenes by base induced inter and intramolecular C-S and C-C bond formation: a non-catalytic approach
Authors:Pushyamitra MishraHardesh K Maurya  Brijesh KumarVishnu K Tandon  Vishnu Ji Ram
Institution:a Department of Chemistry, Lucknow University, Lucknow 226007, India
b Division of SAIF, Central Drug Research Institute, Lucknow 226001, India
c Department of Organic Chemistry, Universität Saarland, Saarbrücken 66123, Germany
Abstract:An efficient and concise one pot synthesis of highly functionalized thiophenes and pyranone fused thiophenes has been delineated through base induced ring transformation of suitably functionalized 2H-pyran-2-ones by ethyl thioglycolate by inter and intramolecular C-S and C-C bond formation.
Keywords:Thiophene  Thieno[3  2-c]pyran-4-one  Ethyl thioglycolate  Ring transformation reaction  Thienylacetonitrile
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