Synthesis of 2,3-diaryl-5H-imidazo[2,1-a]isoindol-5-ones via the one-pot reaction of 1,2-diketones, 2-formylbenzoic acids, and ammonium acetate |
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| Authors: | Maryam Sadat Hosseini-ZareMohammad Mahdavi Mina SaeediMehdi Asadi Shahrzad JavanshirAbbas Shafiee Alireza Foroumadi |
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| Affiliation: | a Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran
b Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medicinal Sciences, Tehran 14176, Iran |
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| Abstract: | We describe a new one-pot synthesis of 2,3-diaryl-5H-imidazo[2,1-a]isoindol-5-ones via the reaction of 1,2-diketones, 2-formylbenzoic acids, and ammonium acetate in acetic acid under reflux conditions and in the absence of a catalyst. |
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| Keywords: | Imidazo[2,1-a]isoindol-5-one 1,2-Diketones Ammonium acetate |
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