A multicomponent synthesis of triazinane diones |
| |
Authors: | Groenendaal Bas Vugts Danielle J Schmitz Rob F de Kanter Frans J J Ruijter Eelco Groen Marinus B Orru Romano V A |
| |
Institution: | Department of Chemistry & Pharmaceutical Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081 HV, Amsterdam, The Netherlands orru@few.vu.nl. |
| |
Abstract: | An efficient, one-pot synthetic protocol toward triazinane diones, a rather unexplored class of heterocyclic scaffolds combining phosphonates, nitriles, aldehydes, and isocyanates is described. The optimization of the reaction, synthesis of a small library of different triazinane diones, as well as alternative routes toward the triazinane dione scaffold are discussed. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|