| 环糊精衍生物对野黄芩素的增溶作用 |
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| 引用本文： | 杨霞,杨波,廖霞俐,张淼,刘振坤.环糊精衍生物对野黄芩素的增溶作用[J].光谱实验室,2012,29(3):1330-1333. |
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| 作者姓名： | 杨霞 杨波 廖霞俐 张淼 刘振坤 |
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| 作者单位： | 昆明理工大学生命科学与技术学院 昆明市呈贡新区景明南路727号 650500 |
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| 基金项目： | 国家自然科学基金，云南省应用基础研究基金 |
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| 摘 要： | 采用相溶解度法考察了25℃时羟丙基-β-环糊精(HP-β-CD)、乙二胺-β-环糊精(en-β-CD)、二乙烯三胺-β-环糊精(dien-β-CD)对野黄芩素的增溶作用,得到野黄芩素在环糊精及其衍生物中的相溶解度曲线均为AL型,说明其与环糊精的包合比为1:1。结果表明3种环糊精主体化合物对野黄芩素的增溶作用大小为:en-β-CD>dien-β-CD>HP-β-CD。
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| 关 键 词： | 环糊精 野黄芩素 相溶解度 增溶作用 |
Solubilization of Scutellarein by Different Type of Cyclodextrin Derivatives |
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| YANG Xia
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YANG Bo
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LIAO Xia-Li
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ZHANG Miao
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LIU Zhen-Kun.Solubilization of Scutellarein by Different Type of Cyclodextrin Derivatives[J].Chinese Journal of Spectroscopy Laboratory,2012,29(3):1330-1333. |
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| Authors: | YANG Xia YANG Bo LIAO Xia-Li ZHANG Miao LIU Zhen-Kun |
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| Institution: | (Faculty of Life Science and Technology,Kunming University of Science and Technology,Kunming 650500,P.R.China) |
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| Abstract: | Solubilization of Scutellarein at 25℃ by β-cyclodextrin derivatives including hydroxypropyl-β-cyclodextrin(HP-β-CD),ethylenediamine-β-cyclodextrin(en-β-CD) and diethylenetriamine-β-cyclodextrin(dien-β-CD) were determined by phase solubility method.The results showed that the phase solubility curves of Scutellarein in three different cyclodextrins were all AL-type,thus the inclusion ratio of Scutellarein versus cyclodextrins was 1∶1.The solubilizations of the three β-cyclodextrin hosts were sorted as follows: en-β-CD>dien-β-CD>HP-β-CD. |
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| Keywords: | Cyclodextrin Scutellarein Phase Solubility Solubilization |
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