| Synthesis of 5,6-Dihydro-OSW-1 and Its Antitumor Activities |
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| 作者姓名： | 邓乐华 吴浩 俞飚 蒋满荣 吴家睿 |
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| 作者单位： | [1]StateKeyLaboratoryofBio-organicandNaturalProductsChemistry,ShanghaiInstituteofOrganicChemistry,ChineseAcademyofSciences,Shanghai200032,China [2]InstituteofBiochemistryandCellBiology,ShanghaiInstituteforBiologicalSciences,ChineseAcademyofSciences,Shanghai200031,China |
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| 基金项目： | the National Natural Science Foundation of China (Nos. 20372070 and 29925203). |
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| 摘 要： | 5,6-Dihydro-OSW-1 (1) was synthesized following our previous procedure for the total synthesis of OSW-1. This compound demonstrated slightly stronger potency than that of OSW-1 against the growth of cancer cells.
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| 关 键 词： | 合成 5 6-二氢-OSW-1 抗癌活性 类似物 |
Synthesis of 5,6-Dihydro-OSW-1 and Its Antitumor Activities |
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| DENG,Le-Huaa Wu,Haob YU,Biao,a JIANG,Man-Rongb WU,Jia-Ruib a State Key Laboratory of Bio-organic and Natural Products Chemistry.Synthesis of 5,6-Dihydro-OSW-1 and Its Antitumor Activities[J].Chinese Journal of Chemistry,2004,22(9):994-998. |
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| Authors: | DENG Le-Huaa Wu Haob YU Biao a JIANG Man-Rongb WU Jia-Ruib a State Key Laboratory of Bio-organic and Natural Products Chemistry |
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| Institution: | DENG,Le-Huaa Wu,Haob YU,Biao*,a JIANG,Man-Rongb WU,Jia-Ruib a State Key Laboratory of Bio-organic and Natural Products Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032,China b Institute of Biochemistry and Cell Biology,Shanghai Institute for Biological Sciences,Chinese Academy of Sciences,Shanghai 200031,China |
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| Abstract: | 5,6-Dihydro-OSW-1 (1) was synthesized following our previous procedure for the total synthesis of OSW-1. This compound demonstrated slightly stronger potency than that of OSW-1 against the growth of cancer cells. |
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| Keywords: | dihydro-OSW-1 analog synthesis anti-tumor |
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