Portable paper‐based device for quantitative colorimetric assays relying on light reflectance principle |
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| Authors: | Bowei Li Longwen Fu Wei Zhang Weiwei Feng Lingxin Chen |
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| Institution: | 1. Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, P. R. China;2. Graduate University of Chinese Academy of Sciences, Beijing, P. R. China |
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| Abstract: | This paper presents a novel paper‐based analytical device based on the colorimetric paper assays through its light reflectance. The device is portable, low cost (<20 dollars), and lightweight (only 176 g) that is available to assess the cost‐effectiveness and appropriateness of the original health care or on‐site detection information. Based on the light reflectance principle, the signal can be obtained directly, stably and user‐friendly in our device. We demonstrated the utility and broad applicability of this technique with measurements of different biological and pollution target samples (BSA, glucose, Fe, and nitrite). Moreover, the real samples of Fe (II) and nitrite in the local tap water were successfully analyzed, and compared with the standard UV absorption method, the quantitative results showed good performance, reproducibility, and reliability. This device could provide quantitative information very conveniently and show great potential to broad fields of resource‐limited analysis, medical diagnostics, and on‐site environmental detection. |
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| Keywords: | Colorimetric assay Light reflectance Metal ions Nitrite Paper‐based microfluidic device Point‐of‐care |
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