酶催化脱保护方法及在生物有机化学中的应用

系统地介绍和评述了近年来氨基、羧基、巯基和羟基等到基团的酶催化脱保护方法的进展。由于酶催化脱保护方法具有反应条件温和(中性，水溶液)、选择性和专一性高、副反应少等到优点，故在多肽缀合物、糖等敏感多官能团化合物的研究中有很广阔的应用前景。

Application of enzymatic deprotection reactions to bioorganic chemistry

Recent advances is enzymatic deprotection reactions of amino groups, carboxyl groups, thiol groups and hydroxyl groups are reviewed. Enzymatic deprotection techniques, which have the advantages of high selectivity, high specificity under mild conditions and in aqueous solutions, are being evaluated as potential methods for synthesizing the sensitive compounds such as peptide conjugates and carbohydrates.