Facile synthesis of 3,4-dihalofurans via electrophilic iodocyclization |
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| Authors: | Yang Fan Jin Tienan Bao Ming Yamamoto Yoshinori |
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| Affiliation: | Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8548, Japan. |
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| Abstract: | ![]()
A facile, efficient, and general synthetic method for 3,4-dihalofurans has been developed via the electrophilic iodocyclization of various 4-hydroxy-2-but-2-yn-1-ones. The use of MeOH as a solvent is crucial for the efficient chemoselective synthesis of the corresponding 3,4-dihalofurans. |
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