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The radioprotective and prophylactic properties of biologically active substances prepared by supercritical fluid extraction from pine shoots |
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| Authors: | V. F. Ur’yash A. E. Gruzdeva A. V. Ur’yash A. A. Silkin N. Yu. Kokurina |
| Affiliation: | 1.Research Institute of Chemistry,Nizhni Novgorod State University,Nizhni Novgorod,Russia;2.OOO “Grande”,Nizhni Novgorod,Russia;3.Mount Sinai Medical Center,Miami Beach,USA;4.Nizhni Novgorod State University,Nizhni Novgorod,Russia |
| Abstract: | The radioprotective properties of a substance from pine shoots prepared by supercritical fluid extraction with carbon dioxide were studied for a model of an experimental bone-marrow radiation sickness form. Experiments were performed for white nonlinear mice. The CO2 extract of pine shoots was shown to possess radioprotective properties. The extract was subjected to pre-clinical tests for Wistar line male rats with respect to its antiatherogenic and antioxidative action in the creation of experimental hyperlipemia. |
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