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Hexafluoroacetone as Protecting and Activating Reagent. A New Approach to N-linked Glycopeptoids
Authors:Klaus Burger  Christoph B?ttcher  Lothar Hennig and Samy A Essawy
Institution:(1) Institute for Research in Biomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028 Barcelona, Spain;(2) CIBER-BBN, Networking Centre on Bioengineering Biomaterials and Nanomedicine, Barcelona Science Park, University of Barcelona, Baldiri Reixac 10, 08028 Barcelona, Spain;(3) Department of Organic Chemistry, University of Barcelona, Mart? i Franqu?s 1-11, 08028 Barcelona, Spain
Abstract:A preparatively simple synthesis of N-linked glycopeptoids starting from iminodiacetic acid and glycosylamines, using hexafluoroacetone as protecting and activating reagent is described.
Keywords:
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