超声引导椎旁神经阻滞治疗带状疱疹后遗神经痛的疗效及可行性分析

本文对超声引导椎旁神经阻滞治疗带状疱疹后遗神经痛(post-herpetic neuralgia,PHN)的疗效及可行性进行了分析。研究对象为2015年12月～2017年12月于我院就诊的94例PHN患者,按就诊顺序随机均分为两组,对照组给予普瑞巴林常规治疗,观察组在此基础上联合超声引导椎旁神经阻滞治疗,连续治疗4周。本文比较了治疗前、治疗1周、2周、4周后的匹兹堡睡眠质量指数(PSQI)评分、疼痛视觉模拟(VAS)评分,并评价了治疗后的综合疗效,记录了治疗期间发生不良反应情况。结果显示,较治疗前,治疗1周、2周、4周后两组VAS评分均逐渐降低,且观察组治疗后各时间点的VAS评分显著低于对照组,差异具有统计学意义(P<0.05);较治疗前,两组治疗1周、2周、4周后PSQI评分均逐渐降低,且观察组治疗后各时间点的PSQI评分显著低于对照组,差异具有统计学意义(P<0.05);观察组治疗总有效率为89.36%,对照组为78.72%,观察组显著高于对照组,差异具有统计学意义(P<0.05);两组治疗期间各项不良反应发生率差异无统计学意义(P>0.05)。本文证实了超声引导椎旁神经阻滞治疗PHN能显著改善患者神经疼痛症状,提升睡眠质量,同时具有安全性保障。

Efficacy and Feasibility Analysis of Ultrasound-guided Paravertebral Nerve Block for the Treatment of Post-herpetic Neuralgia

To analysis the efficacy and feasibility of ultrasound-guided paravertebral nerve block for the treatment of post-herpetic neuralgia, ninety-four patients with PHN admitted to our hospital from December 2015 to December 2017 were selected as the study subjects. They were randomly divided into two groups according to the order of treatment. The control group received routine treatment with pregabalin, and the observation group combined routine treatment with ultrasound-guided paravertebral nerve block therapy for 4 weeks. Pittsburgh sleep quality index (PSQI) scores and pain visual analogue (VAS) scores before treatment, 1 week, 2 weeks, and 4 weeks of treatment were compared. The combined efficacy after treatment was evaluated, and the adverse reactions during treatment were recorded. The results showed that compared with pre-treatment, the VAS scores of the two groups were gradually decreased at 1 week, 2 weeks, and 4 weeks of treatment, and the observation group was significantly lower than the control group at each time point after treatment, the difference was statistically significant (P<0.05). The PSQI scores of the two groups were gradually decreased at 1 week, 2 weeks, and 4 weeks of treatment, and the observation group was significantly lower than the control group at each time point after treatment, the difference was statistically significant (P<0.05). The total effective rate was 89.36% in the observation group and 78.72% in the control group, and the difference was statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Ultrasound-guided paravertebral nerve block for PHN can significantly reduce neuropathic pain in patients, improve sleep quality, and has security guarantee.