| 几个新型噁唑硼烷的制备与应用 |
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| 引用本文： | 荣国斌,李新明,张勇.几个新型噁唑硼烷的制备与应用[J].有机化学,2000,20(5):769-772. |
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| 作者姓名： | 荣国斌 李新明 张勇 |
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| 作者单位： | 华东理工大学化学系,上海,200237 |
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| 摘 要： | 以(1S,2S)-2-氨基-1-(4-硝基苯)-1,3-丙二醇为原料，得到四种噁唑硼烷，原?
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$601$ATwonewtypesof1,3,2-oxaborolidineswerepreparedfrom(1S,2S)-2-amino-1-(4-nitrophenyl)-propane-1,3-diolandusedascatalystsintheasymmetricreductionofacetophenone.Theinfluenceoftemperatureaswellastheeffectofthestructureofcatalystontheenantioselectivityisdiscussed.Theoriginoftheproducts'configurationalisexplored.
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| 关 键 词： | 噁唑 硼杂环化合物 恶唑硼烷 不对称反应 催化剂 还原反应 前手性酮 硼烷类 |
| 修稿时间： | 1999年12月6日 |
The preparation and application of two new types of oxazaborolidines |
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| RONG Guo-Bin,LI Xing-Ming,ZHANG Yong.The preparation and application of two new types of oxazaborolidines[J].Chinese Journal of Organic Chemistry,2000,20(5):769-772. |
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| Authors: | RONG Guo-Bin LI Xing-Ming ZHANG Yong |
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| Institution: | East China Univ of Sci Tech., Dept Chem.Shanghai(200237) |
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| Abstract: | Two new types of 1,3,2- oxaborolidines were prepared from (1S,2S) -2- arnino - 1 - (4 - nitro-phenyl) - propane - 1,3 - diol and used as catalysts in the asymmetric reduction of acetophenone.
The influence of temperature as well as the effect of the structure of catalyst on the enantioselectivity is discussed. The origin of the products' configurational is explored. |
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| Keywords: | oxazaborolidine asymmetric catalytic reduction prochiral ketone |
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