首页 | 本学科首页   官方微博 | 高级检索  
     


Quasispecies distribution of Eigen model
Authors:Chen Ji  Li Sheng  Ma Hong-Ru
Affiliation:Department of Physics, Shanghai Jiaotong University, Shanghai 200240, China
Abstract:We have studied sharp peak landscapes of the Eigen model from anew perspective about how the quasispecies are distributed in thesequence space. To analyse the distribution more carefully, we bringin two tools. One tool is the variance of Hamming distance of thesequences at a given generation. It not only offers us a differentavenue for accurately locating the error threshold and illustrateshow the configuration of the distribution varies with copyingfidelity $q$ in the sequence space, but also divides the copyingfidelity into three distinct regimes. The other tool is thesimilarity network of a certain Hamming distance $d_{0}$, by which wecan gain a visual and in-depth result about how the sequences are distributed. We find that there are several local similarity optimaaround the centre (global similarity optimum) in the distribution ofthe sequences reproduced near the threshold. Furthermore, it isinteresting that the distribution of clustering coefficient $C(k)$follows lognormal distribution and the curve of clusteringcoefficient $C$ of the network versus $d_{0}$ appears to be linear near the threshold.
Keywords:Eigen model   sharp peak landscapes  similarity network   clustering coefficient
本文献已被 维普 等数据库收录!
点击此处可从《中国物理》浏览原始摘要信息
点击此处可从《中国物理》下载免费的PDF全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号