Retention characteristics of fluorinated bonded silica phase in reversed-phase liquid chromatography |
| |
| Authors: | Jinno K. Nakamura H. |
| |
| Affiliation: | (1) School of Materials Science, Toyohashi University of Technology, 441 Toyohashi, Japan |
| |
| Abstract: | Summary Fluorinated bonded silica has been evaluated as a packing material in reversed-phase liquid chromatography (RPLC) with polycyclic aromatic hydrocarbons, chlorinated benzenes and substituted benzenes as sample probes. The bonded material is useful as a reversed-phase stationary phase and for polar compounds it offers a specific selectivity not found with octadecylsilica (ODS) phases. The phase also retains non-planar compounds more than planar molecules. The results can be explained by conformational differences between ODS and the fluorinated bonded phase by MM2 calculation. |
| |
| Keywords: | Column liquid chromatography Fluorinated chemically bonded silica Aromatic compounds Molecular shape vs. retention |
| 本文献已被 SpringerLink 等数据库收录！ |
