Bidesmosidic Oleanane Saponins from Xerospermum noronhianum |
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| Authors: | Tan Pei Jean Khozirah Shaari Christian Paetz Intan Safinar Ismail Faridah Abas Nordin H. Lajis Viqar Uddin Ahmad |
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| Affiliation: | 1. Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM, Serdang, Malaysia (phone: +60?389466776;2. fax: +60?389435380);3. Max‐Planck‐Institute for Chemical Ecology, Hans‐Kn?ll‐Stra?e 8, DE‐07745 Jena;4. H.?E.?J. Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan |
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| Abstract: | Three new oleanane‐type triterpenoid saponins, 3‐O‐(α‐L ‐rhamnopyranosyl(1→2)‐β‐D ‐fucopyranosyl)‐28‐O‐{[α‐L ‐rhamnopyranosyl(1→2)] [β‐D ‐fucopyranosyl(1→6)]‐β‐D ‐glucopyranosyl} oleanolic acid ( 1 ), 3‐O‐[α‐L ‐rhamnopyranosyl(1→3)‐β‐D ‐fucopyranosyl]‐28‐O‐[α‐L ‐rhamnopyranosyl(1→4)‐β‐D ‐glucopyranosyl] oleanolic acid ( 2 ), and 3‐O‐{α‐L ‐rhamnopyranosyl(1→2)‐[3′,4′‐diacetoxy‐β‐D ‐fucopyranosyl]}‐28‐O‐[α‐L ‐rhamnopyranosyl(1→2)‐β‐D ‐glucopyranosyl] oleanolic acid ( 3 ) have been isolated from the stems of Xerospermum noronhianum. The structures of the saponins were determined as a series of bidesmosidic oleanane saponins based on spectral evidence. The anticholinesterase activity of the saponins 1 – 3 was also evaluated. |
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| Keywords: | Xerospermum noronhianum Triterpenoids Oleanolic acid Saponins |
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