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Alkaloids from the Roots of Stemona tuberosa
Authors:Jun‐Ping Hu  Dong‐Hui Yang  Wen‐Han Lin  Shao‐Qing Cai
Affiliation:1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, P.?R. China, (phone/fax: +86‐10‐82801693);2. School of Pharmaceutical Sciences, Xinjiang Medical University, Urumqi 830054, P.?R. China
Abstract:Four new alkaloids, didehydrotuberostemonine A ( 1 ), stemoninone ( 2 ), tuberostemospiroline ( 3 ), and tuberostemonine L ( 4 ), together with seven known alkaloids, were isolated from the roots of Stemona tuberosa. Their structures were elucidated on the basis of spectroscopic analysis. The known alkaloids were identified as 2‐oxostenine ( 5 ), tuberostemonine ( 6 ), sessilifoliamide H ( 7 ), tuberostemonone ( 8 ), didehydrotuberostemonine ( 9 ), bisdehydrostemoninine ( 10 ), and tuberostemoamide ( 11 ).
Keywords:Stemona tuberosa  Alkaloids  Didehydrotuberostemonine A  Stemoninone  Tuberostemospiroline  Tuberostemonine L
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