Lingshuine,an Unexpected Passerini Product from the Hainan Sponge Axinyssa variabilis |
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| Authors: | Duo‐Qing Xue Ernesto Mollo Guido Cimino Yue‐Wei Guo |
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| Affiliation: | 1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, P.?R. China (phone: +86‐21‐50805813);2. Istituto di Chimica Biomolecolare‐CNR, I‐80078, Pozzuoli (Naples) |
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| Abstract: | Lingshuine ( 1 ), a novel sesquiterpene amide, along with three known N‐containing compounds, 2 – 4 , have been isolated from the Hainan sponge Axinyssa variabilis. The structure of 1 was elucidated by detailed analysis of the spectroscopic data and by chemical methods. Lingshuine represents the first example of a Passerini product formed during the isolation process. |
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| Keywords: | Axinyssa variabilis Passerini reaction Bisabolenes Sesquiterpenes Lingshuine Marine sponges Isolation artifacts |
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