Phenylethyl Glycosides from Digitalis lanata |
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| Authors: | Hasan K?rm?z?bekmez Engin Celep Milena Masullo Carla Bassarello Erdem Ye?ilada Sonia Piacente |
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| Institution: | 1. Yeditepe University, Faculty of Pharmacy, Department of Pharmacognosy, TR‐34755 Kay??da??, ?stanbul, Turkey, (phone: +90‐216‐5780000‐3050;2. fax: +90‐216‐5780068);3. Salerno University, Department of Pharmaceutical Sciences, Via Ponte Don Melillo, I‐84084 Fisciano‐Salerno |
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| Abstract: | Three new phenylethyl glycosides, 3′′′′‐O‐methylmaxoside (=2‐(3,4‐dihydroxyphenyl)ethyl O‐β‐D ‐glucopyranosyl‐(1→3)‐O‐β‐D ‐glucopyranosyl‐(1→6)]‐4‐O‐(E)‐feruloyl‐β‐D ‐glucopyranoside; 1 ), digilanatosides A (=2‐(3,4‐dihydroxyphenyl)ethyl O‐6‐O‐(E)‐sinapoyl‐β‐D ‐glucopyranosyl‐(1→3)‐4‐O‐(E)‐caffeoyl‐β‐D ‐glucopyranoside; 2 ), and digilanatoside B (=2‐(3,4‐dihydroxyphenyl)ethyl O‐6‐O‐(E)‐p‐coumaroyl‐β‐D ‐glucopyranosyl‐(1→3)‐4‐O‐(E)‐caffeoyl‐β‐D ‐glucopyranoside; 3 ) were isolated from the aerial parts of Digitalis lanata, along with two known phenylethyl glycosides, purpureaside A and maxoside, a phenylpropanoid glucose ester, 1‐O‐(E)‐feruloyl‐β‐glucopyranose, a benzoquinolethanoid glucoside, cornoside, a cardenolide, lanatoside C, a furostane‐type steroidal saponin, purpureagitoside, and a disaccharide, sucrose. Their structures were elucidated on the basis of spectroscopic evidence (1D‐ and 2D‐NMR, and HR‐MALDI‐MS). |
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| Keywords: | Digitalis lanata Phenylethyl glycosides Glycosides Methylmaxoside Digilanatosides A and B |
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