| Design, synthesis and in vitro evaluation of phenylbenzamidine derivatives as SSRIs |
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| 引用本文： | Jing Yang Xiaofang Wang Hui Wen Fang Qin Guang Zhong Yang. Design, synthesis and in vitro evaluation of phenylbenzamidine derivatives as SSRIs[J]. 中国化学快报, 2007, 18(7): 814-816. DOI: 10.1016/j.cclet.2007.05.024 |
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| 作者姓名： | Jing Yang Xiaofang Wang Hui Wen Fang Qin Guang Zhong Yang |
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| 作者单位： | Jing Yang，Xiaofang Wang，Hui Wen，Fang Qin，Guang Zhong Yang * Institute of Materia Medica，Peking Union Medical College and Chinese Academy of Medical Science，Beijing 100050，China |
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| 基金项目： | 国家自然科学基金;北京市自然科学基金 |
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| 摘 要： | A series of phenylbenzamidine analogs were synthesized and tested for their biological activities of inhibiting the reuptake of 5- HT. All of them were new compounds, and their structures were confirmed by 1HNMR, MS and XRD.
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| 关 键 词： | SSRIs XRD 苯基苄脒 合成 结构分析 |
| 收稿时间： | 2007-04-06 |
| 修稿时间： | 2007-04-06 |
Design, synthesis and in vitro evaluation of phenylbenzamidine derivatives as SSRIs |
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| Jing Yang,Xiaofang Wang,Hui Wen,Fang Qin,Guang Zhong Yang. Design, synthesis and in vitro evaluation of phenylbenzamidine derivatives as SSRIs[J]. Chinese Chemical Letters, 2007, 18(7): 814-816. DOI: 10.1016/j.cclet.2007.05.024 |
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| Authors: | Jing Yang Xiaofang Wang Hui Wen Fang Qin Guang Zhong Yang |
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| Affiliation: | Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Science, Beijing 100050, China |
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| Abstract: | A series of phenylbenzamidine analogs were synthesized and tested for their biological activities of inhibiting the reuptake of 5- HT. All of them were new compounds, and their structures were confirmed by 1HNMR, MS and XRD. |
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| Keywords: | SSRIs Phenylbenzamidine XRD |
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