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Polycavernoside C and C2, the new analogs of the human lethal toxin polycavernoside A, from the red alga, Gracilaria edulis |
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| Authors: | Mari Yotsu-Yamashita Kazumi Abe Kenshu Fujiwara |
| Institution: | a Graduate School of Agricultural Science, Tohoku University, Tsutsumidori-Amamiya, Aoba-ku, Sendai 981-8555, Japan b Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo 060-0810, Japan c Japan Food Research Laboratories, Tama Laboratory, 6-11-10 Nagayama, Tama-shi, Tokyo 206-0025, Japan |
| Abstract: | Two new analogs of the human lethal toxin polycavernoside A, polycavernoside C and C2 (0.1-0.2 mg for each), were isolated from the red alga, Gracilaria edulis. The relative stereostructure of polycavernoside C and the absolute structure of polycavernoside C2 were determined by spectroscopic analysis and synthesis of the model of their aglycon. |
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