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A rapid and versatile synthesis of novel pyrimido[5,4-b]carbazoles |
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| Authors: | Anna Caruso Jean-Charles Lancelot Maria Stefania Sinicropi Aurélien Lesnard |
| Institution: | a Université de Caen Basse-Normandie, U.F.R. des Sciences Pharmaceutiques, Centre d'Etudes et de Recherche sur le Médicament de Normandie, UPRES EA-4258, FR CNRS INC3M, Boulevard Becquerel, 14032 Caen Cedex, France b Dipartimento di Scienze Farmaceutiche, Università della Calabria, 87036 Arcavacata di Rende Cosenza, Italy c Chemistry Department, Faculty of Science, Assiut University, 71516 Assiut, Egypt |
| Abstract: | A one-pot synthesis of 2-dialkylamino-5,11-dimethyl-6H-pyrimido5,4-b]carbazol-4(3H)-ones, as new ellipticine analogs, starting from aminocarbazole derivatives is reported. This method allowed us to prepare a library of potentially useful compounds in the pharmaceutical field. |
| Keywords: | Fused carbazoles Pyrimidocarbazoles Ellipticine analogs Multi-component reactions |
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