DNA‐Cleavage by Fullerene‐Based Synzymes

Efficient cleaving of DNA oligonucleotides by a water‐soluble fullerene main‐chain polymer is demonstrated following a facile routine of monitoring the reaction by UV‐vis spectroscopy and separating the cleaved fractions by membrane filtration. A small quantity of the fullerene derivative could cleave a large excess of the oligonucleotide under ambient light conditions, leading to cleaved DNA in quantitative yields.