Chiral ligand-controlled asymmetric conjugate addition of lithium amides to enoates |
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Authors: | Doi Hirohisa Sakai Takeo Iguchi Mayu Yamada Ken-ichi Tomioka Kiyoshi |
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Affiliation: | Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan. |
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Abstract: | ![]() The external chiral ligand-controlled asymmetric conjugate addition reaction of lithium amides with alpha,beta-unsaturated esters provided beta-amino esters in high yields and high enantioselectivities. |
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