Synthesis of poison-frog alkaloids 237D, 207A, and two congeners of 235B' for evaluation to inhibitory effect of nicotinic acetylcholine receptors |
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| Authors: | Toyooka Naoki Kawasaki Masashi Nemoto Hideo |
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| Affiliation: | Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugatani, Toyama 930-0194, Japan. toyooka@ms.toyama-mpu.ac.jp |
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| Abstract: | ![]()
Enantioselective synthesis of the poison-frog alkaloids 237D, 207A, and two congeners of 235B' has been achieved. The absolute stereochemistry of 237D was determined to be 5S, 8S, 9R by the present synthesis. |
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