New Dolabellane Derivatives from the Brown Alga Dictyota pardalis |
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| Authors: | Anthony D Wright Gabriele M Knig Otto Sticher Paolo Lubini Patrick Hofmann Max Dobler |
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| Institution: | Anthony D. Wright,Gabriele M. König,Otto Sticher,Paolo Lubini,Patrick Hofmann,Max Dobler |
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| Abstract: | Reinvestigation of the brown alga Dictyota pardalis f. pseudohamata CRIBB led to the crystallization of 1 and to the isolation of the two new dolabellane derivatives 2 and 3 . X-Ray analysis of 1 and 2 , together with detailed 1D-and 2D-NMR studies on 2 and 3 , allowed their structures to be elucidated as (1R*,3S*,7S*,11R*,4Z)-dolabella-4,8(17), 12(18)-triene-3,7-diol ( 1 ), (1R*,3S*,4S*,7S*,8S*,11R*,14R*,12E)-3,4:7,8-diepoxydolabe11-12-ene-14, 18-diol ( 2 ), and (1R*,3S*,4S*,7S*,8S*,11R*,14R*)-3,4:7,8-diepoxy-l,4,8,12,12-pentamethylbicyclo9. 3. 0]tetra-decan-14-ol( 3 ). |
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