Efficient synthesis of phosphorus-containing dendrimers capped with isosteric functions of amino-bismethylene phosphonic acids |
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Authors: | Olivier Rolland,Cé dric-Olivier Turrin,Gé rard Bacquet,Mary Poupot,Jean-Pierre Majoral |
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Affiliation: | a CNRS, LCC (Laboratoire de Chimie de Coordination), 205, route de Narbonne, F-31077 Toulouse, France b Université de Toulouse, UPS, INPT, LCC, F-31077 Toulouse, France c Rhodia, Centre de Recherches d’Aubervilliers 52 rue de la Haie Coq, F-93308 Aubervilliers Cedex, France d INSERM 563, Centre de Physiopathologie de Toulouse-Purpan, Hôpital Purpan, BP 3048, F-31024, Toulouse Cedex 03, France |
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Abstract: | An efficient synthetic strategy to synthesize phosphorus-containing dendrimers capped with isosteric acid functions derived from tyramine is described. The method is demonstrated on a first generation dendrimer that can be easily capped with 12 amino(bismethylene) sulfonic acids and amino(bismethylene) carboxylic acids that are strict analogs of the corresponding amino(bismethylene) phosphonic acids. |
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Keywords: | Dendrimers Phosphonate Sulfonate Carboxylate Polyanions |
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