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Novel and efficient supramolecular synthesis of pyrroles in the presence of β-cyclodextrin in water |
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| Authors: | K Ramesh K Karnakar G Satish Y V D Nageswar |
| Institution: | CSIR-Natural Product Chemistry, Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500-007, India |
| Abstract: | A simple and efficient synthesis of highly substituted pyrroles was achieved in water medium via multi-component strategy, using amine, DMAD/DEAD as well as phenacyl bromide catalyzed by β-CD. Utilizing this protocol various pyrrole derivatives were synthesized in good to excellent yields. |
| Keywords: | Amine DMAD/DEAD Phenacyl bromide Water Recyclability β-Cyclodextrin |
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