Self-assembling a molecular pegboard |
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Authors: | Lund Kyle Liu Yan Lindsay Stuart Yan Hao |
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Institution: | Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287, USA. |
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Abstract: | This paper describes the design, construction, and application of a self-assembled, chemically addressable DNA nanogrid composed of DNA tiles of nanometer dimensions. This self-assembled structure permits precise placement of molecules at predetermined locations on a "molecular pegboard". We used the indexed DNA nanogrids to identify single molecules of DNA that hybridize at particular locations. |
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