Honeycomb-patterned films of polystyrene/poly(ethylene glycol): preparation,surface aggregation and protein adsorption |
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Authors: | LingShu Wan BeiBei Ke XiaoKai Li XiangLin Meng LuYao Zhang ZhiKang Xu |
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Institution: | (1) Key Laboratory of Macromolecular Synthesis and Functionalization of Ministry of Education, Institute of Polymer Science and State Key Laboratory of Chemical Engineering, Zhejiang University, Hangzhou, 310027, China |
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Abstract: | Highly ordered honeycomb-patterned polystyrene (PS)/poly(ethylene glycol) (PEG) films were prepared by a water-assisted method
using an improved setup, which facilitated the formation of films with higher regularity, better reproducibility, and larger
area of honeycomb structures. Surface aggregation of hydrophilic PEG and adsorption of bovine serum albumin (BSA) on the honeycomb-patterned
films were investigated. Field emission scanning electron microscopy (FESEM) and atomic force microscopy (AFM) were used to
observe the surface morphologies of the films before and after being rinsed with water. As confirmed by the FESEM images and
the AFM phase images, PEG was enriched in the pores and could be gradually removed by water. The adsorption of fluorescence-labeled
BSA on the films was studied in visual form using laser scanning confocal microscopy. Results clearly demonstrated that the
protein-resistant PEG was selectively enriched in the pores. This water-assisted method may be a latent tool to prepare honeycomb-patterned
biofunctional surfaces.
Supported by the National Natural Science Foundation of China (Grant No. 50803053), the National Natural Science Foundation
of China for Distinguished Young Scholars (Grant No. 50625309), the National Postdoctoral Science Foundation of China (Grant
Nos. 20070421172 & 20081466) and the National Undergraduate Innovative Test Program |
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Keywords: | honeycomb-patterned film water-assisted method polystyrene poly(ethylene glycol) surface aggregation |
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