Isolation, structure determination, and synthesis of galaxamide, a rare cytotoxic cyclic pentapeptide from a marine algae Galaxaura filamentosa期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Isolation, structure determination, and synthesis of galaxamide, a rare cytotoxic cyclic pentapeptide from a marine algae Galaxaura filamentosa

Authors:	Xu Wen-Jie Liao Xiao-Jian Xu Shi-Hai Diao Jian-Zhong Du Bin Zhou Xu-Long Pan Shan-Shan

Affiliation:	Institute of Hydrobiology, Jinan University, Huangpu Road West 601, Guangzhou, Guangdong 510632, People's Republic of China.

Abstract:	Galaxamide (1), a rare cyclic pentapeptide, was isolated from the marine algae Galaxaura filamentosa. A preliminary bioassay of Galaxamide showed remarkable in vitro antiproliferative activities against GRC-1 and HepG2 cell lines. The first total synthesis of the cyclic peptide was achieved for further biological evaluation.

Keywords:
本文献已被 PubMed 等数据库收录！