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Synthesis of 2,3-disubstituted derivatives of pyrano-, thiopyrano-, and benzoannelated pyrido[2,3-b]thieno[3,2-d]pyrimidines
Authors:E. G. Paronikian  Sh. F. Akopian  A. S. Noravian
Affiliation:(1) A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences, Republic of Armenia, Erevan, 375091, Armenia
Abstract:
A new methods have been developed for the synthesis of condensed pyrido[2,3-b]thieno[3,2-d]pyrimidines based on cyclic derivatives of 4-cyanopyridine-3-thiones. The presence of two different reactive functional groups NH2 and CONH gives the possibility of carrying out different conversions of thieno[2,3-b]pyridines. __________ Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, 1245–1252, August, 2008.
Keywords:N-alkyl-4-oxothieno[3,2-d]pyrimidine-2-thiones  pyrano(thiopyrano)(4′  ,3′  :4,5]pyrido[2,3-b]-thieno[3,2-d]pyrimidines  pyridothieno[3,2-d]pyrimidines  pyrimido[5′  ,4′  :2,3]thieno[2,3-c]isoquinolines  4-cyanopyridin-3-thiones
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