| Abstract: | ![]()
The structure of carquejol is amended to that of cis-3-hydroxy-o-mentha-1(7),4,8-triene; the chirality has been confirmed as 2 R, 3 S by correlation with the (?)-cis-o-menthane obtained from carquejol and that from (+)-verbenene of known absolute configuration. The two double bonds of the dihydrocarquejol system ( 15 and 16 ) constitute a helical system, that especially in the case of the acetate ( 16 ) fixes the isopropenyl group in such a way that a very high Δ? value in the CD. curve is observed. The conformational significance of this phenomenon is discussed. |
