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Efficient conversion of aldoximes to nitriles using phosphoric acid diethyl ester 2-phenylbenzimidazol-1-yl ester |
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| Authors: | Nagnnath D Kokare Devanand B Shinde |
| Institution: | (1) Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, 431004, India;(2) Wockhardt Research Centre, Aurangabad, Maharashtra, 431210, India |
| Abstract: | Abstract Aromatic aldoximes were converted to the corresponding nitriles in good to excellent yields by employing phosphoric acid diethyl
ester 2-phenylbenzimidazol-1-yl ester as reagent. The method was equally effective for oximes bearing electron-donating and
electron-withdrawing substituents.
Graphical Abstract
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| Keywords: | Aldehydes Aldoximes N-Hydroxy-2-phenylbenzimidazole Nitriles |
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