Design,synthesis, and application of chiral electron-poor guanidines as hydrogen-bonding catalysts for the Michael reaction |
| |
| Authors: | Karen Thai Michel Gravel |
| |
| Affiliation: | Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, SK, Canada S7N 5C9 |
| |
| Abstract: | ![]()
The first chiral electron-poor guanidine organocatalysts were synthesized. The presence of a tunable electron-withdrawing group on the guanidine moiety allows for the modulation of the catalysts’ activity. The application of this new class of organocatalysts to the Michael reaction is demonstrated. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
