| 高分子支撑液膜固定化细胞甾体△1-脱氢转化的研究 |
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| 引用本文： | 何炳林,李乃宏,姜坪.高分子支撑液膜固定化细胞甾体△1-脱氢转化的研究[J].高等学校化学学报,1986,7(10):941. |
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| 作者姓名： | 何炳林 李乃宏 姜坪 |
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| 作者单位： | 南开大学高分子化学研究所 |
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| 摘 要： | 研究了高分子支撑液膜固定化细胞的制备、性质以及影响其催化氢化可的松→去氢氢化可的松生物转化的各种因素,并与经典珠状包埋法固定细胞的转化作用进行了比较。结果表明前者的△1-脱氢速率和产物转化率均高于后者。在所使用的条件下二者未见机械强度方面明显差别。
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| 收稿时间： | 1985-04-25 |
Study of Steroid Transformation Catalyzed by Polymer-Supported Liquid Membrane Encapsulated Cells |
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| He Binglin,Li Naihong,Jang Ping.Study of Steroid Transformation Catalyzed by Polymer-Supported Liquid Membrane Encapsulated Cells[J].Chemical Research In Chinese Universities,1986,7(10):941. |
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| Authors: | He Binglin Li Naihong Jang Ping |
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| Institution: | Polymer Chemistry Institute of Nankai University, Tianjin |
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| Abstract: | This paper describes the preparation and properties of polymer-supported liquid membrane-immobilized cells of Arthrobactcr simplex which catalyze the transformation of cortisol into prednisolone.The transforming activities of cells immobilized by this method was compared with that of cells immobilized by traditional entrapment method.The results showed that the former were obviously higher than those of the latter,and there was nosapprent difference of mechanical strength between the former and the latter on our operational conditions.The various factors affecting the transformation were studied as well. |
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