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Synthesis of two regiospecific isomers of monotosyl-γ-cyclodextrin
Authors:Keiko Takahashi  Kenjiro Hattori
Institution:(1) Department of Industrial Chemistry, Faculty of Engineering, Tokyo Institute of Polytechnics, 243-02 Atsugi, Kanagawa, Japan
Abstract:Tosylation of gamma-cyclodextrin in an aqueous alkaline solution gave two regiospecific isomers (2-monotosyl-gamma-cyclodextrin(1) and 6-monotosyl-gamma-cyclodextrin(2)), that could recognize and catalyze small sized guest molecules; 2-monotosyl-gamma-CD recognized small sized guest molecules more effectively than did 6-monotosyl-gamma-CD.
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